PBS203

Cancer Metabolism Target

  • Significant factors of tumor microenvironment
  • PRIINT Understanding & Targeting pancreatic cancer cell metabolism
source : Nature Reviews Cancer 2020, 20, 516

Target expression

  • Target expression of orthotopic model of pancreatic cancer
  • Colon cancer, Prostate cancer, Head & Neck cancer, Lymphoma
Analyzing orthotopic tissue biopsy
  • Normal
  • Cell line 1Orthotopic transplant model tissue
  • Cell line 2Orthotopic transplant model tissue
  • Cell line 3Orthotopic transplant model tissue
Target expression of patient tissue
  • Colorectal cancer
  • Breast cancer
  • Prostate cancer
  • Lung cancer
  • Testis cancer
source : Nature Reviews Cancer 2020, 20, 516
Target validation
  • Anti-cancer effect to novel target of pancreatic cancer
  • Validation of orthotopic pancreatic model with reference
Anti-cancer Effect of target of colon cancer
Anti-cancer Effect of Pancreatic Cancer Orthotopic Model
Hit to lead screening
In Vitro : Cell Line based pharmacology & Screening
Library screening
Virtual screening